Workshop

Clinical Study: Sample Size Calculation


Einstein A March 20, 2019 2:00 PM - 3:00 PM

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Fabien Leclercq

Sample Size Calculation is performed to determine the minium number of subjects for adequate study power. Key concepts: alpha and beta risks, baseline incidence, population variance and effect size.

– Observational studies: sample size based on unilateral or bilateral confidence interval
– Comparative studies: sample size based on comparison of proportions (normality assumption)

In both cases we will work on case studies, build statistical hypothesis and use sample size calculator.

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